![]() We have added new information while striving to emphasize important principles and not increase the size of the book. Examples of areas in which our understanding has grown impressively since the last edition of this book include innate immunity and the functions of Toll-like receptors, the role of chemokines and their receptors in maintaining the functional architecture of lymphoid tissues, the functions of adapter proteins and kinase pathways in immune cell signal transduction pathways, and the basis of natural killer cell recognition of ligands. It is remarkable to us that new paradigms continue to be established in the field and unifying principles continue to emerge from analysis of complex molecular systems. The fifth edition of this book has been extensively revised to incorporate new discoveries in immunology and the constantly growing body of knowledge. I SAUNDERS I An Imprint of Elsevier Science Baker, MA Alexandra Baker, MS, CMI DNA Illustrations, Inc. Lichtman, MD, PhD Associate Professor of Pathology Harvard Medical School Brigham and Women's Hospital Boston, Massachusetts Abbas, MBBS Professor and Chair Department of Pathology University of California-San Francisco School of Medicine San Francisco, CaliforniaĪndrew H. Cellular and Molecular Immunology Fifth Edition Abul K.
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